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Long-term or high-dose PPI use has been associated with increased risk of B12 deficiency, particularly in patients with additional risk factors, though the absolute risk remains relatively modest
The formulation appears to support metabolic function and energy production, which has been helpful in maintaining consistency with diet and activity levels

The SURMOUNT-1 trial reported 15 to 22 percent mean body weight loss on tirzepatide over 72 weeks

Van Der Weyden, M

doi: 10.1152/physrev.00003.2018
