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10.1242/JCS.240929 22

Tirzepatide (Mounjaro, Zepbound): The SURMOUNT-1 trial enrolled 2,539 participants

Elevated NNMT activity has been associated with increased fat accumulation, reduced metabolic efficiency, and impaired cellular energy production

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The first generation of anti-tau antibodies, most of which targeted the proteins polymerization-driving N terminus, failed in clinical trials