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Hep-G2 cells with MIA3 overexpression were subjected to RNA-seq, and the downstream target gene CHAC1 (glutathione-specific -glutamyl cyclotransferase 1) was selected according to the results of the volcano map of gene enrichment

Post-1-h knockdown and post-24-h mortality were recorded and analyzed

Patients often present with confusion, nausea, and vomiting as well as an elevated anion gap metabolic acidosis

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