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Individual variation in MC4R sensitivity exists

Therefore, acute phase reactants like procalcitonin and C-reactive protein (CRP) have been used to differentiate between bacterial infection and DRESS syndrome, finding that patients with concomitant infectious processes have elevated levels of reactants, using a cut-off for procalcitonin of 1.33 ng/ml and for CRP of 10.83 ng/ml 9

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Gut microbiota: primary producers of trimethylamine Gut microbiota, particularly Firmicutes and Proteobacteria , are key mediators of TMA production through distinct enzymatic pathways (51, 52)

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If patients carry only one SMN2 copy and show any symptoms (probable SMA type 0), initiation of treatment is left to the discretion of the physicians