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Recent research suggests semaglutide drugs may be linked to serious eye conditions, including non-arteritic anterior ischemic optic neuropathy (NAION)

A key point is that the activation of GLP-1R can produce specific effects on different organs by addressing age-related diseases in various manners, such as enhancing cognitive function and addressing vascular issues caused by age-related brain changes, while simultaneously raising the likelihood of renal dysfunction in aging organs

Revising it for intellectual content: C

Tirzepatide was approved by the Food and Drug Administration in May 2022 for the treatment of T2D, and later in October received Fast Track designation for treatment of obesity

[DOI] [PMC free article] [PubMed] [Google Scholar] 26.He L., Zhang S., Zhang X., Liu R., Guan H., Zhang H

Specifically, this paper delved into an overview of GLP-1s role at the physiological level as a modulator of the incretin effect, which is an important hormonal pathway whose dysregulation was explained to be implicated in the pathogenesis of T2DM