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Umemiya, M

del Ro et al., 2006

The main ligand for these selectins is the P-selectin glycoprotein ligand (PSGL)-1 (CD162) expressed on neutrophils and certain endothelial cells

Endothelial cells comprise the inner monolayer of blood vessels that forms a barrier between the artery wall and circulating blood is responsible for regulating vascular tone, regulation of hemostatic properties on the vascular surface, and determining blood-tissue/brain permeability (Paschos and FitzGerald, 2010)