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Giustarini, D., Milzani, A., Dalle-Donne, I

Tan et al., reported that FIIN-2, an irreversible covalent FGFR inhibitor, formed the covalent binding mode at the Cys477 residue of FGFR4 in the DGF-out conformation (96)

doi: 10.4158/ep171983.Or 100 YuXMJaskula-SztulRAhmedKHarrisonADKunnimalaiyaanMChenH

[DOI] [PubMed] [Google Scholar] 64.Berk M, Turner A, Malhi GS, Ng CH, Cotton SM, Dodd S, Samuni Y, Tanious M, McAulay C, Dowling N, Sarris J, Owen L, Waterdrinker A, Smith D, Dean OM

Systematically evaluate the differential neurotoxicity of MPs/NPs based on physical and chemical properties Future research must systematically compare how MPs/NPs propertiesincluding size, shape, surface charge, polymer type, and degradation stateinfluence PD-related pathways

Correcting these cofactors helps optimize neurotransmitter synthesis, methylation, and overall metabolism