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Hao T, Du X, Yang S, Zhang Y, Liang F

*Correspondence: Fengming Yi, [email protected] These authors have contributed equally to this work and share first authorship ORCID: Fengming Yi, orcid.org/0000-0002-9417-644X Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

These changes may be one of the important causes of aging or functional impairment of tissues and organs ( Skin aging and cell senescence Skin aging occurs when there is an excessive buildup of senescent cells, which hampers the macrophage-dependent clearance mechanism due to SASP inhibition

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