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doi: 10.2337/dc18-0777

GSH is essential for cell survival as demonstrated by observations that glutamate cysteine ligase (GCL) knockout mice die from massive apoptotic cell death [117], and that the knockdown of GCL in distinct cell types induces time-dependent apoptosis [118,119]

The chelate complex (the chelating agent bound to the metal ion) is then excreted in the urine

Pharm Pharmacol Commun 6(11):517520 Panda S, Kar A (2001) Inhibition of T3 production in levothyroxine-treated female mice by the root extract of Convolvulus pluricaulis

Secondly, superoxide anion is produced by a family of NADPH oxidases (NOX/DUOX), comprised of seven isoforms: NOX1NOX5 and DUOX1-DUOX2 [6]
