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653 In a randomized pilot study, curcumin (180 mg/day) for 8 weeks as an add-on therapy enhanced working memory and lowered IL-6 and hs-CRP levels in patients with schizophrenia ( n = 12)

In addition to its pro-differentiating actions, nicotinamide promotes neuronal survival, especially in oxidative stress environments, through various pathways, such as maintenance of protein kinase B (akt)-dependent phosphorylation of forkhead transcription factor (FOXO3a)

It plays a crucial role in breaking down H 2 O 2 produced during cellular respiration into oxygen and water (Figure 1)

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Compound 13, an Alpha1-selective small molecule activator of ampk, inhibits helicobacter pylori-induced oxidative stresses and gastric epithelial cell apoptosis