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Verma AK, Singh S, Rizvi SI (2023) Aging, circadian disruption and neurodegeneration: Interesting interplay

With the rise of Arabidopsis as a study system, and notably genome sequencing, the pathway and its genes were characterized at the molecular genetic level, revealing (or confirming) that all four enzymes were encoded by more than one gene, thus explaining the presence of the enzyme activities in several compartments (Table 1)

Many peptide- and protein-based drugs are pH-sensitive and prone to hydrolysis, deamidation, or oxidation outside their optimal pH range, which can compromise therapeutic efficacy (Illum, 2003

Glutamine Carrier or SLC1A5_Var SLC1A5_Var is a splice variant of the cell membrane sodium-dependent neutral amino acid transporter SLC1A5, which facilitates the transport of glutamine from the cytosol into the mitochondrial matrix [104]

10.3390/nu15173730

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