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a transcription initiation site (conveniently defined by mapping with nuclease SI) as well as protein binding domains (consensus sequences) responsible for the binding of RNA polymerase

175 ZIP4 is particularly important for zinc uptake and is closely related to the process

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Free Radic Biol Med 78:4255

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265,266 Additionally, as a key source of intracellular zinc, MTs play a vital role in the catalytic activation and structural stability of metalloenzymes