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Amyloid precursor protein haploinsufficiency preferentially mediates brain iron accumulation in mice transgenic for the Huntington's disease mutation
E., Cameron M
In mice, MTHFR deficiency decreases SAM, increases SAH and reduces global DNA methylation, directly associating impaired MTHFR flux to a hypomethylated genome (102,103)
Chemoinformatics analysis identifies cytotoxic compounds susceptible to chemoresistance mediated by glutathione and cystine/glutamate transport system xc
Hays PL, Kawamura S, Deng XH, Dagher E, Mithoefer K, Ying L, Rodeo SA
10.1186/s12929-024-01075-w 146
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