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These factors induce oxidative stress, endoplasmic reticulum (ER) stress, or DAMPs release, resulting in inflammation, immune dysregulation, and melanocyte destruction ( NLRP1 and IFIH , may predispose individuals to activate innate immune pathways more readily

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Following these steps can help make the process consistent and more comfortable

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Mitochondria continuously function to metabolize oxygen and generate ROS (Figure 2)

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doi: 10.1080/19490976.2025.2486512 179 YeH.LiuX.GuanK.MaY.LiuR.LiuY.et al

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