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The co-transfer of nave CD4 + CD45RB hi and regulatory CD4 + Foxp3 GFP T cells as well as depletion Foxp3 DTR T cells in T-transferred Rag 1 -/- mice confirmed the suppressive effect of CDD-2103 on colitis activity, which was associated with an increase in the Treg cell population in the colon

Kenny, Anne M

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