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The neurotoxic mechanisms of AMPHs and cathinones are not fully understood but involve excitotoxicity caused by excessive glutamate release, blood-brain barrier damage, mitochondrial dysfunction, neuroinflammation, DNA damage, and oxidative stress
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Phase 1: Consultation and Assessment (Week 0) Comprehensive history and physical examination Review of prior imaging, surgical reports, and treatment history Discussion of goalsreturn to sport, pain reduction, GI symptom resolution, etc
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