glutathione production in cancer cells Role of Cancer: From Mechanisms to Therapies Glutathione Depletion and Stalwart Anticancer

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Transcription of ARE results in the production of numerous antioxidant enzymes, such as SOD, GPx, glutathione-s-transferase(GSTr), catalase (CAT), heme-oxygenase-1 (HO-1), NADPH-quinone-oxidoreductase (NQO-1), phase II enzymes of drug metabolism and heat shock proteins (HSP)

24 h later, they were decapitated and the brains were immediately removed and stored for further biochemical analyses

HFD-induces GSH deficiency and epigenetically alters VD-biosynthesis pathway genes

Ferroptosis is a form of regulated cell death induced by iron-dependent lipid peroxidation, and it has been studied extensively since its discovery in 2012