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This can happen due to low levels of intrinsic factors in the digestive system, digestive conditions, or following a plant-based diet
coli grown on a minimal growth medium using a carbonic anhydrase-based sensor is 20 pM, which is, gratifyingly, just inside the range predicted by the model (Figure 8A)

Archived from the original on 14 June 2014

Subsequently, the L-isomer is converted to succinyl-CoA by methylmalonyl-CoA mutase (MUT), a mitochondrial enzyme that requires the active coenzyme form of vitamin B12, adenosylcobalamin (Takahashi-Iiguez et al

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PubMed 3.Prkacin I et al