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Funding This work was supported by the Doctoral Research Initiation Fund of Wannan medical college (Young and Middle-aged Scientific Research Fund of Wannan Medical College) (WYRCQD2023028), Anhui Province Engineering Research Center for dental materials and application (Grant No: 2024AMCD06), Program for Excellent Sci-tech innovation Teams of Universities in Anhui Province (Grant No: 2023AH010073)

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Abstract Apigenin (C 15 H 10 O 5 , API) is a natural flavonoid widely found in vegetables, fruits, and plants such as celery, oranges, and chamomile