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Nov 1996;30(11):1255-1262

New York, NY: Oxford Research Encyclopedia of Neuroscience

Hetz C, Papa FR

These findings suggest that grape seed PCs can substantially reduce oxidative stress resulting from UVB exposure while providing protective effects against skin damage caused by UVB radiation ( In conclusion, the aforementioned research indicates that PCs can mitigate oxidative stress associated with aging skin by neutralizing ROS accumulation, suppressing lipid peroxidation caused by ROS, and enhancing overall antioxidant capacity, as shown in Table 2

Therefore, activating GPX4 and GSH to inhibit ferroptosis is an attractive option for cardiac disease therapy (Fig

927 These results suggest that HDAC3 maintains iron homeostasis through the Hippo/YAP pathway and might represent a target to reduce ferroptosis in iron overload-related diseases