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In lipid environments, tocopherols act as major inhibitors of lipid peroxidation, while carotenoidssuch as -caroteneserve dual functions: physically quenching singlet oxygen in the photosynthetic apparatus and modulating adaptive signaling pathways

Biochim Biophys Acta 1797:11951202 Cronan JE (2016) Assembly of lipoic acid on its cognate enzymes: an extraordinary and essential biosynthetic pathway

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Because high levels of phospholipid hydroperoxides promote ferroptosis 10 , our results from SOD1 G93A GPX4 mice thus support the notion that ferroptosis is a key mode of cell death in motor neuron degeneration of SOD1 G93A mice

Additionally, Fourier-transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), and stability studies were conducted, in the present study, to evaluate the prepared nanodispersions