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BBC3/PUMA, BCL2 binding component 3

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Hg is a potent and apparently irreversible inhibitor of the selenoenzymes, glutathione peroxidases (GPX), and thioredoxin reductases (TXNRD) that are important antioxidants, each with a selenocysteine (SeCys) at the active site

This enzyme contains a bound zinc ion at its active site

The mechanism of action is multifactorial, directly or indirectly upregulating cell growth, proliferation, survival, angiogenesis, and anti-inflammation pathways

Choline is reacted with acety-CoA to form the neurotransmitter acetyl-choline