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When glutathione levels drop, the immune system effectively "loses its brakes," allowing for the overproduction of pro-inflammatory cytokines like Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNF-)

Within the testis, the main cells involved in the production of testosterone and spermatogenesis are the interstitium-located Leydig cells and the seminiferous tubules-located Sertoli cells and germ cell lines

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showed expression of toll-like receptor 9 (TLR9) in intact erythrocytes, mediating the capability to bind bacterial and plasmodial cell-free DNA, as well as synthetic CpG DNA [55]