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Though this is speculative rather than evidence-based

NNMT inhibition with 5-Amino-1MQ reduced white adipose tissue mass by ~35% in diet-induced obese mouse models without suppressing food intake, suggesting energy expenditure modulation
Transfer: Cusipata Phulawasipata We continue climbing for 1 additional hour to Phulawasipata (4,200 masl), the base camp and starting point for the trek to Vinicunca

[DOI] [PubMed] [Google Scholar] 205.Argyropoulos G, Brown AM, Willi SM, et al

But does the science actually support them

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