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doi: 10.1016/j.cmet.2007.05.003 90 MuiseESAzzolinaBKuoDWEl-SherbeiniMTanYYuanXet al

Malabsorption (insufficient absorption of vitamin B12 in the intestine) due to insufficient production of intrinsic factor (a protein produced in the lining of the stomach that is needed to absorb vitamin B12), disorders in the end section of the ileum (part of the small intestine), such as sprue, fish tapeworm infestation or blind loop syndrome (change in the course of the intestine after gastric surgery)

Building on this, the use of multi-platforms, as well as the addition cutting-edge technologies such as single-cell analysis could be instrumental

Evid Based Complement Alter Med 2020(1):6127327 Yaghoobi R, Soghrati M, Pazyar N, Parvin N (2018) Investigating the effect of 1% curcumin gel and placebo on patients with plaque psoriasis

Treating the underlying cause: Supplementing B12 alone without addressing the underlying gut or pancreatic condition is only a partial solution