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10.1038/s41392-024-02095-6

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10.1016/j.bbrc.2013.08.001 144 YoshimuraT.ShibataN.HamanoY.YamanakaK

DJ-1 functions as a bona fide negative modulator of ferroptosis by sustaining S-adenosyl homocysteine hydrolase activity through altering its interaction with the negative regulator adenosylhomocysteinase like protein 1, thereby maintaining the transsulfuration pathway-mediated biosynthesis of homocysteine and subsequent GSH synthesis (157)