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HepaRG cells (8000 cells/25 L/well) or PHHs (Hu8163, 17,500 cells/25 L/well) were seeded in collagen I-coated 384-well white flat-bottom plates (Corning, catalog: 354665)

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They're thought to help the body break down and utilize fats more effectively, and support the liver in its crucial detoxification jobs

Key findings include a 70% increase in skin thickness after 12 days of topical application, wrinkle volume reduction of 55.8% and depth reduction of 32.8% in clinical studies, and accelerated wound healing across multiple models (Pickart et al., 2018)

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Further studies are needed to determine whether other factors may also be involved