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no completed efficacy trials of the TB-500 fragment

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10.1007/s10815-012-9715-0 36 DadouneJ

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The trial lasted 68 weeks and included 3417 individuals who were randomized to either CagriSema, its individual components or placebo [125]

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This is due to low absorption in the intestine, and breakdown by enzyme activity

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10.1210/jcem.81.2.8636250 49 UngvariZ.TarantiniS.KissT.WrenJ

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