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Notably, specific pharmacological interventions have shown potential in mitigating immunosenescence via T cell modulation

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However, these basic findings potentially provide clues for sex-dependent etiologies of diseases that involve oxidative stress

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In its invasive hyphal form, Candida penetrates the intestinal epithelium and releases more than 70 identified mycotoxins including acetaldehyde, gliotoxin, and candidalysin that trigger systemic inflammation, impair mitochondrial function, disrupt neurotransmitter synthesis, and compromise the integrity of the gut barrier, producing a multi-system clinical presentation that spans gastrointestinal, neurological, endocrine, dermatological, and immunological domains

Mol Psychiatry (2008) 13:83357.10.1038/mp.2008.65 104 LawrenceNSWilliamsAMSurguladzeSGiampietroVBrammerMJAndrewCet alSubcortical and ventral prefrontal cortical neural responses to facial expressions distinguish patients with bipolar disorder and major depression