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Translation to clinical use requires demonstrating superiority over existing therapies and establishing long-term safety through rigorous trials

The authors also demonstrated no significant advantage of one agent over another and recommended a choice based on comfort level, the experience of the dermatologist, and the safest strength [107]

The ghrelin receptor pathway (GHS-R1a), activated by both endogenous ghrelin and synthetic GHRPs like Ipamorelin, operates through Gq proteins, mobilizing intracellular calcium and activating protein kinase C (PKC)

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Chirality 2021;33(10):597-601