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Aged mice were divided into control and treatment groups, with the latter receiving intraperitoneal injections of FOXO4-DRI at doses of 0.5 mg/mL and 5 mg/kg every other day for 30 days, while controls received PBS

This is a meaningful finding given how often steroid injections precede the chronic tendon injuries patients bring to us

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However, one CBER-issued warning letter, O3UV, LLC (July 7, 2025), was for a CBER-regulated device, which we have excluded for the purposes of the analyses in this article

A standard GLP diet and fresh water were provided ad libitum
