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Toxicol Ind Health 33:454468

10.1159/000021313 Boebel KP, Baker DH: Blood and liver concentrations of glutathione, and plasma concentrations of sulfur-containing amino acids in chicks fed deficient, adequate, or excess levels of dietary cysteine

Final Thoughts In clinical trials, patient safety is not merely a regulatory checkbox but a crucial element that underpins the ethical, scientific, and operational success of research

Preclinical studies demonstrated that itaconate, a structural analog of succinate, inhibits ICL through covalent interaction with the catalytic cysteine residues (Cys191 of ICL1 and Cys215 of ICL2) of M.tb [30]

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however, these proteins can be found on other membranes, including those of the ER and mitochondria