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doi: 10.3390/su152216053 190 WenQ.ZhangL.ZhaoF.ChenY.SuY.ZhangX.et al

Ribas V, Drew BG, Zhou Z et al (2016) Skeletal muscle action of estrogen receptor is critical for the maintenance of mitochondrial function and metabolic homeostasis in females

Nebivolol decreases oxidative stress in essential hypertensive patients and increases nitric oxide by reducing its oxidative inactivation
When it comes to dosage this is relative and will depend on your body weight and needs after a physicians evaluation

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