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Description
Despite the clear connection between UPR mt activation and longevity in the context of mitochondrial translation inhibition, UPR mt activation is also observed in short-lived mitochondrial mutants, and constitutively active alleles of ATFS-1 exhibit reduced lifespan 15

GSTs, glutathione-S-transferases

It was first found in the segment polarity of Drosophila, where it helps to establish anterior and posterior polarities

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ATM activation in the presence of oxidative stress

Lv H, Zhen C, Liu J, Yang P, Hu L, Shang P
