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10.1016/j.bcp.2011.06.039 240 PatelA

For tested athletes, it is banned by WADA (S0)

Greinacher A, Thiele T, Warkentin TE, Weisser K, Kyrle PA, Eichinger S

9 SNRIs and SSRIs Studies suggest that diabetic peripheral neuropathic pain is related to an unbalanced release of norepinephrine and serotonin from neurons

Animals were housed under a 12 h light/dark cycle at room temperature (22 2 C) and constant humidity levels at around 5070%, with food and water provided ad libitum in a specific pathogen free (SPF) environment

Various contacts occur between PLP and the enzyme, including the Schiff base linkage with the active site Lys300, the hydrogen bonding between N1 of PLP and conserved Asp271, and hydrogen bonding between the phosphate moiety of PLP and Thr330, Gly128, Ala129, and several water molecules
