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In addition, analysis at the cellular level showed that the reduction in body fat was associated with decreased lipid content and smaller fat droplet size in adipocytes in the 3T3-L1 cell line [49]

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Conclusion Cutaneous toxicities derived from targeted therapies, ADCs, and immunotherapy are relatively frequent events presenting as a broad and heterogeneous clinical spectrum of AEs with significant impact on both patients quality of life and the continuity of anticancer treatment

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