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These findings highlight the potential of exosomes from various stem cell sources as promising therapeutic strategies for SCI, operating through multiple mechanisms such as promoting angiogenesis, modulating inflammation and oxidative stress, inhibiting apoptosis, and supporting axonal regeneration, as detailed in Table 4

Myeloid-derived suppressor cells as regulators of the immune system

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Given the lack of a guiding pathogenesis and the dominance of highly lucrative (but largely ineffective) immunosuppressive drugs, a collective descent into a normalization of deviance within this field appears to have been inevitable

"Mechanisms of autoregulation of C3G, activator of the GTPase Rap1, and its catalytic deregulation in lymphomas." Sci