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Among the cytokines, tumor necrosis factor (TNF) and IL-1 regulate leak pathway by promoting occludin endocytosis and MLCK activation [19, 23]
The hyperdense osmiophilic deposits are pathognomonic, and hence the term dense deposit disease
PAI-1 in Tissue Fibrosis
[DOI] [PubMed] [Google Scholar] 20.Abu-Own A, Schurr JH, Coleridge Smith PD
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Since association with Pol II and the elongation complex is dependent on the SPOC domain, direct interaction of DIDO1 and DIDO2 with Pol II is improbable
