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Therefore it is possible that zinc treatment leads to decreased enterocyte copper uptake through competition for uptake through ZIP4, although CTR1 is still likely to be the main copper transporter in this cell type based on knockout studies (Nose et al., 2006)

Another example is in Saccharomyces cerevisiae , where the iron metabolism is regulated by the transcription factors Aft1/Aft2 and Yap5, in accordance to the available iron levels [24, 36]

doi: 10.1038/srep34477 73 ChenY.StricklandM

Purification and properties of S-formylglutathione hydrolase from human liver

Key Features Naturally occurring tripeptide: Gly-His-Lys complexed with copper (Cu) Molecular weight: 404.96 Da

Correct mutations and sequences were confirmed for all constructs by sequencing both strands