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Phase I/II Study of PR104, a Bioreductive Prodrug, in Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML) Using Patient-Specific Adaptive Dose Selection

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4 and additional file 3), as we previously observed using another multispecific GST substrate, MCB [11]

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Nat Rev Immunol 8:411420 Avissar NE, Sax HC, Toia L (2008) In human entrocytes, GLN transport and ASCT2 surface expression induced by short-term EGF are MAPK, PI3 K, and Rho-dependent

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In addition, artesunate activated the AKT and HO-1 signaling pathways, decreased the expression of TUNEL and Bax proteins, and increased Bcl-2 expression to alleviate acute lung injury induced by intestinal ischemia/reperfusion in mice (Ji et al., 2023)

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