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The efficacy results were so impressive that an Independent Data Safety and Monitoring Board recommended the studys early termination

investigated the eryptosis rate in healthy RBCs treated with different concentrations of IL-6, IL-1, urea, and p -cresol, comparable to their plasma levels in CKD patients, at different time points, and evaluated the cytotoxic effect on RBCs by an in vitro setting

doi: 10.1371/journal.pone.0124599 42 KimYSUnnoTKimBYParkMS

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