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The assays optimal pH is 7.0, which is close to physiological pH (7.4), thereby simulating antioxidant activity under realistic conditions

doi: 10.1016/j.freeradbiomed.2020.03.008 35 HenkelRSandhuISAgarwalA

Healthy lifestyle recommendations: Do the beneficial effects originate from NAD+ amount at the cellular level

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1, 2, 3, 4 This has motivated research into lifestyle interventions and drugs for prevention and treatment of these diseases

The present observational study reveals, for the first time, that, after a dry dive test at depth in a hyperbaric chamber to mimic in-depth sea diving, highly trained divers manifest: (1) cognitive impairment coupled to low circulating and/or saliva content of dopamine, glutamate, and BDNF