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If "mitochondrial signaling in aging" is the framing, MOTS-c is the literature favorite

Several limitations should be considered when interpreting the findings of this review

It may interact with alpha-adrenergic and dopaminergic systems, with benefits for the healing of gastrointestinal ailments [12]

Alkali Halides in Water: Ion-Solvent Correlations and Ion-Ion Potentials of Mean Force at Infinite Dilution

Ghrelin, a gastrointestinal hormone, regulates energy balance and lipid metabolism