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In individuals with type 2 diabetes, increased IL-6 levels have been suspected as a cause of lowered GSH levels (Lagman et al., 2015)
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While little is known about the role of GSTA4 in cancer, particularly in colorectal cancer, previous studies have demonstrated that transfection of primary cell lines with human GSTA4-expressing plasmids causes cellular transformation and immortalization via upregulation of transforming growth factor, cyclin-dependent kinase 2, and protein kinase C beta II and downregulation of p53 (35)

Cohesin relocation from sites of chromosomal loading to places of convergent transcription

Combined administration of NAC and DMSA after arsenic exposure led to a significant reduction of oxidative stress biomarkers, as well as to removal of arsenic from organs [120]
