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Cosmetic effects like Ozempic face (a thinner, gaunt appearance from rapid fat loss in the face) and temporary hair shedding have also been reported

Sesame also offers a weight loss program that provides both branded weight loss and diabetes drugs and compounded semaglutide injections

Establishing consistent sleep-wake times, creating a dark and cool bedroom environment, and limiting screen exposure before bed can improve sleep quality and support healthy GLP-1 activity

Changes in liraglutide-induced body composition are related to modifications in plasma cardiac natriuretic peptides levels in obese type 2 diabetic patients

Aleniglipron (Structure Therapeutics) is heading into Phase 3 in mid-2026

"While these changes are most pronounced on the face, they can also be seen in other parts of the body, including neck and buttocks, with sagging and wrinkling." GLP-1 medications may also contribute to hormonal and metabolic changes that can affect rapidly growing tissues like hair and nails