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The medication reduced 17-24% of body weight with consistent use over 48 weeks

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As of the present moment, there are no published studies that have investigated the impact of melatonin on A burden specifically in humans

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Transcriptomic analysis of iSPNs at the pre-symptomatic stage showed de-regulation of metabolic pathways, including upregulation of Gsto2, encoding glutathione S-transferase omega-2 (GSTO2)

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