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Bhattacharya PT, Misra SR, Hussain M
Cell 3 , 10761087 (2004)
Theoretically, the senescence process entails the complications of fueling inflammation and disrupting the tissues structure and function
First, optimal dosing in humans remains undefined, with current practice based primarily on extrapolation from animal studies and anecdotal clinical experience rather than formal dose-finding studies
Toxicol Appl Pharmacol
Intriguingly, extinction of methamphetamine self-administration reverses the downregulation of mGlu 2 in striatal regions, whereas the effect persists in the case of abstinence
