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The average rigidity duration was 41 minutes, and 68% of the volunteers reported elevated sexual desire

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While this observational data has limitations and does not establish causation, the mechanistic basis for the difference is plausible: synthetic progestins like medroxyprogesterone acetate bind progesterone receptors with different affinity and also carry partial androgenic and glucocorticoid activity, whereas micronized progesterone behaves more selectively [5]