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Lee RJ, Hempel J, Tenharmsel A, Liu T, Mathe AA, Klock A (2012)

Henry FE, Wang X, Serrano D, Perez AS, Carruthers CJL, Stuenkel EL, Sutton MA (2018) A unique homeostatic signaling pathway links synaptic inactivity to postsynaptic mTORC1

Given the above, employing bioinformatics approaches, efforts were made in this study (a) to identify potential GPX and APX genes/proteins from 18 different plant species, (b) to analyze their exon/intron organization, (c) to provide detailed information about their physico-chemical properties, (d) to identify conserved motif signatures of GPX and APX, (e) to construct their phylogenetic trees and 3D models, (f) to generate protein-protein interaction networks, and finally (g) to analyze GPX and APX gene expression profiles

Of note, in the B16F10 melanoma model, a high density of effector T cells in the tumor promoted LEC apoptosis via the IFN- signaling pathway (92)

These effects could potentially worsen the condition of IBD (69)
