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Cancer 12 (5), 335340
10.1002/cbdv.201900051 40 EngwaG

Together, these data suggest that lung tumor tissues have increased Glo1 expression and production of LGSH to detoxify methylglyoxal

These mechanisms were previously investigated using a rat model, revealing changes in synaptic plasticity genes, with more pronounced alterations observed in the ventral cochlear nucleus

While cancers derived from tissues with normal NAPRT levels are entirely dependent on the NAD + salvage pathway for survival
Jacques PF, Hartz SC, Chylack LT, McGandy RB, Sadowski JA
